Pol Vilaseca, Kenneth A. Dawson, Giancarlo Franzese
It is now well accepted that cellular responses to materials in a biological
medium reflect greatly the adsorbed biomolecular layer, rather than the
material itself. Here, we study by molecular dynamic simulations the
competitive protein adsorption on a surface (Vroman-like effect), i.e. the
non-monotonic behavior of the amount of protein adsorbed on a surface in
contact with plasma as a function of contact time and plasma concentration. We
show how the effect can be understood, controlled and inverted.
View original:
http://arxiv.org/abs/1202.3796
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