Wenping Lv, Maodu Chen, Renan Wu
Graphene nanopores fabricated for sensor devices are exhibiting the great potential for the detection of DNA. The molecular dynamics (MD) simulation would be a great help to understand the fundamental aspects of DNA translocation through the graphene nanopores at atomic level. In this paper, the MD simulations were carried out to investigate the impact of nanopores thickness to the DNA translocation in the small aperture range (2 nm - 3 nm). Results showed that the open-pore ionic conductance was sensitive to the thickness of nanopores. The probability of DNA pass through a thick and narrow graphene nanopore could lower than that DNA pass through a thin and wide graphene nanopore. The translocation time of DNA in 2.4 nm graphene nanopores was the most sensitive to the thickness of nanopores. The calculation of potentials of mean force (PMFs) for DNA translocation through 2.4 nm monolayer and bilayer graphene nanopores revealed that the free energy barriers were existed and increased for the thicker graphene nanopore, which could retard the DNA translocation through graphene nanopore as observed for bilayer graphene nanopore comparing monolayer graphene nanopore.
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http://arxiv.org/abs/1210.4993
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