Tuesday, May 7, 2013

1305.1218 (Cornelius S. Bausch et al.)

Guided Neuronal Growth on Arrays of Biofunctionalized GaAs/InGaAs
Semiconductor Microtubes

Cornelius S. Bausch, Aune Koitmäe, Eric Stava, Amanda Price, Pedro J. Resto, Yu Huang, David Sonnenberg, Yuliya Stark, Christian Heyn, Justin C. Williams, Erik W. Dent, Robert H. Blick
We demonstrate embedded growth of cortical mouse neurons in dense arrays of semiconductor microtubes. The microtubes, fabricated from a strained GaAs/InGaAs heterostructure, guide axon growth through them and enable electrical and optical probing of propagating action potentials. The coaxial nature of the microtubes -- similar to myelin -- is expected to enhance the signal transduction along the axon. We present a technique of suppressing arsenic toxicity and prove the success of this technique by overgrowing neuronal mouse cells.
View original: http://arxiv.org/abs/1305.1218

No comments:

Post a Comment