Wednesday, July 3, 2013

1307.0055 (James Wilson et al.)

Single-Base DNA Discrimination via Transverse Ionic Transport    [PDF]

James Wilson, M. Di Ventra
We suggest to discriminate single DNA bases via transverse ionic transport, namely by detecting the ionic current that flows in a channel while a single-stranded DNA is driven through an intersecting nanochannel. Our all-atom molecular dynamics simulations indeed show that the ionic currents of the four bases are statistically distinct, thus offering another possible approach to sequence DNA.
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